Yes. If there is a concern that one of the spouses is using drugs, then a drug test can be ordered in a Missouri divorce or custody case. However, there usually must be children involved and the alleged drug use must have some effect on parenting ability. Also, a drug test isn't often that effective unless it is done with little or no advance notice, and a party to the case should not ask for a drug test unless they are certain that it will come back positive. Otherwise, the requesting party's credibility may be damaged.